Phenol → Phenolphthalein

HRID 1180468Notes

Reaction equation

[C:1]1(=O)[O:6][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[C:12]1([OH:18])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[CH:8]1[CH:9]=[CH:10][C:2]2[C:1]([C:15]3[CH:14]=[CH:13][C:12]([OH:18])=[CH:17][CH:16]=3)([C:15]3[CH:14]=[CH:13][C:12]([OH:18])=[CH:17][CH:16]=3)[O:6][C:4](=[O:5])[C:3]=2[CH:7]=1

Participants

Reactant 2

HCID 996Phenol

HCID 6811Phthalic Anhydride

Product 1

HCID 4764Phenolphthalein

Procedure

Phenolphthalein is synthesized by standard methods involving a condensation reaction with phthalic anhydride and phenol under appropriate reaction conditions. Substituted phenolpthalein derivatives are obtained from the correspondingly substituted phthalic anhydride and in a similar manner.

Workup

customunder appropriate reaction conditions

Sources & evidence

ORD record: ord-f86e105d857f422e8eb3a5f95f0be902
Source dataset: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07282320B2

Reaction notes

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