N-bromobutanimide → HCID 22053533, compound

Participants

Reaction Steps

A mixture of 1-(5-bromo-3-pyridyl)-4-tert-butoxycarbonylhomopiperazine (2.68 g, 7.5 mmol), N-bromosuccinimide (1.34 g, 7.5 mmol) and acetonitrile (75 ml) was stirred for 30 minutes. The crude mixture was evaporated and purified by chromatography on silica gel using ethyl acetate: petroleum (2:1) as solvent. Yield 3.0 g, 92%.

Provenance & Evidence