Sodium Hydroxide → HCID 17953828, compound

Participants

Reaction Steps

A solution of the product of Step 6 (1.0 g, 2.4 mmol) in ethanol (10 ml) containing, 10% aqueous sodium hydroxide solution (10 ml) was heated at 50° C. overnight. On cooling, the solvent was removed in vacuo, the residue dissolved in water and the pH adjusted to 6 with glacial acetic acid and the solvent re-evaporated. The residue was suspended in water (50 ml) and the solid was collected, washed with water and dried over phosphorous pentoxide to give the crude title compound as an off-white solid (0.7 g); MS(AP−) m/e 318 [M−H]−.

Provenance & Evidence