HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxylamine → HCID 9946637, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxylamine | HCID 787 | — |
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | HCID 86588657 | HCID 86588657 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 9946637 | HCID 9946637 | 47.8% |
Reaction Steps
The procedure of Example 13 was followed using the product from Example 18 (230 mg, 0.67 mmol), 1-hydroxybenzotriazol (80 mg, 0.59 mmol), 1-[3-(dimethylamino)-propyl]-3-ethylcarbodimide hydrochloride (132 mg, 0.69 mmol), N-methylmorpholine (0.81 mmol, 0.74 mmol), and hydroxylamine (0.150 ml, 2.45 mmol) in dimethylformamide (5 ml) to give 100 mg (42%) of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07282496B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-ae6056c9b7334bf09c2d81a4ea091c4c |
| Source note | uspto-grants-2007_10 |