3-[4-(1-Amino-cyclobutyl)-phenyl]-6-fluoro-2-phenyl-chromen-4-one → 3-[4-(1-Amino-cyclobutyl)-phenyl]-7-methyl-2-phenyl-7H-pyrano[2,3-e]indazol-4-one

HRID 118060Notes

Reaction equation

HRID 118060 reaction equation
[C:30]([O:31][C:32](=[O:33])[NH:36][C:37]1([c:41]2[cH:42][cH:43][c:44](-[c:47]3[c:48](=[O:67])[c:49]4[c:50]([c:51]5[cH:52][n:53][n:54]([CH3:58])[c:55]5[cH:56][cH:57]4)[o:59][c:60]3-[c:61]3[cH:62][cH:63][cH:64][cH:65][cH:66]3)[cH:45][cH:46]2)[CH2:38][CH2:39][CH2:40]1)([CH3:34])([CH3:35])[CH3:68].[NH2:1][C:2]1([c:3]2[cH:4][cH:5][c:6](-[c:7]3[c:8](=[O:9])[c:10]4[c:11]([cH:12][cH:13][c:14]([F:15])[cH:16]4)[o:17][c:18]3-[c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:25][cH:26]2)[CH2:27][CH2:28][CH2:29]1>>[NH2:36][C:37]1([c:41]2[cH:42][cH:43][c:44](-[c:47]3[c:48](=[O:67])[c:49]4[c:50]([c:51]5[cH:52][n:53][n:54]([CH3:58])[c:55]5[cH:56][cH:57]4)[o:59][c:60]3-[c:61]3[cH:62][cH:63][cH:64][cH:65][cH:66]3)[cH:45][cH:46]2)[CH2:38][CH2:39][CH2:40]1

Participants

3

Reactant 2

HCID 510305983-[4-(1-Amino-cyclobutyl)-phenyl]-6-fluoro-2-phenyl-chromen-4-oneHCID 67067793(1-[4-(7-Methyl-4-oxo-2-phenyl-4,7-dihydro-pyrano[2,3-e]indazol-3-yl)-phenyl]-cyclobutyl)-carbamic acid tert-butyl ester

Product 1

HCID 510299523-[4-(1-Amino-cyclobutyl)-phenyl]-7-methyl-2-phenyl-7H-pyrano[2,3-e]indazol-4-one

Sources & evidence

ORD record
ord-8a73efbc725048a1ad81a72d1ce1e162
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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