Acetone → HCID 11652678, compound

HRID 1180675Notes

Reaction equation

HRID 1180675 reaction equation
[CH2:1]([S:11]([OH:14])(=[O:13])=[O:12])[CH2:2][S:3][S:4][CH2:5][CH2:6][S:7]([OH:10])(=[O:9])=[O:8].[OH-].[Ca+2:16].[OH-].CC(C)=O>O>[CH2:1]([S:11]([O-:14])(=[O:13])=[O:12])[CH2:2][S:3][S:4][CH2:5][CH2:6][S:7]([O-:10])(=[O:8])=[O:9].[Ca+2:16]

Participants

5

Reactant 3

HCID 180AcetoneHCID 656262,2'-Dithiodiethanesulfonic acidHCID 6093208Calcium Hydroxide2×

Product 1

HCID 11652678HCID 11652678, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 2,2′-dithiobis ethane sulfonic acid (2.5 g, containing 9% water, 8.1 mmol) in water (1.0 mL) was titrated with calcium hydroxide (98+% purity, Acros Organics) aqueous solution until the pH of the reaction solution was adjusted to 7.0. Overall, 0.60 g (8.1 mmol) calcium hydroxide was used. Acetone (200 mL) was added to the reaction solution to precipitate the product. The resulting white solid was isolated by filtration and dried under high vacuum to give 2.20 g of product (85% yield). The purity of the product was 97.4% from HPLC analysis.

Workup

  1. customto precipitate the product
  2. customThe resulting white solid was isolated by filtration
  3. customdried under high vacuum

Sources & evidence

ORD record
ord-5b82163779bb4294b4e56d552e66ba53
Source dataset
uspto-grants-2007_10
Patent number
US07282602B2

Reaction notes

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