Acetone → HCID 178512927, compound

Participants

Reaction Steps

A solution of 2,2′-dithiobis ethane sulfonic acid (2.5 g, containing 9% water, 8.1 mmol) in water (1.0 mL) was titrated with L-Arginine (98% purity, Aldrich) aqueous solution until the pH of the reaction solution was adjusted to 7.0. Overall 2.80 g of L-arginine was used. Acetone was added to precipitate the product. The product in aqueous solution was dried under high vacuum to remove as much water as possible. The residue was resuspended in ethanol (30 mL). The white precipitate was isolated by filtration, washed with ethanol (2×30 mL), dried to give 4.93 g of product (97% yield). The purity of the product was 96.3% from HPLC analysis.

Provenance & Evidence