4-Phenylbenzoyl chloride → HCID 58979977, compound

Participants

Reaction Conditions

Reaction Steps

Under nitrogen atmosphere, a mixture of 13 g (0.045 mol) 2,9-bis-(1H-tetrazol-5-yl)-[1,10]phenanthroline and 390 ml pyridine was added to a 250 ml three-necked flask. The mixture was then heated to 50° C., and 46 g (0.21 mol) 4-phenylbenzoyl chloride was then added drop by drop. After the adding, the mixture solution was heated to reflux (110° C.) and stirred overnight. After completion of reaction, as shown in scheme 2, the reaction mixture was cooled to room temperature, filtered. Finally, solids were separated, washed by 100 ml methanol, filtered and purified by column chromatography to obtain white products 2,9-bis-(5-biphenyl-4-yl-[1,3,4]oxadiazol-2-yl)-[1,10]phenanthroline 11 g (0.018 mol, yield 40%). MS(m/z, FAB+), 620, 291, 248, 233, 208, 156, 130, 105.

Provenance & Evidence