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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1180786Generated: October 30, 2026

Cyclobutane-1,1-diyldimethanol → [1-({[5-(4-chlorophenyl)-1-methyl-1H-imidazol-2-yl]sulfanyl}methyl)cyclobutyl]methanol

https://huagongshe.com/reaction/1180786

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutane-1,1-diyldimethanolHCID 4498243—
Reactant5-(4-chlorophenyl)-1-methylimidazole-2-thiolHCID 178479937—
Product[1-({[5-(4-chlorophenyl)-1-methyl-1H-imidazol-2-yl]sulfanyl}methyl)cyclobutyl]methanolHCID 11186355—

Reaction Steps

The title compound was prepared using the same experimental procedure as in example 19a from [1-(hydroxymethyl)cyclobutyl]methanol and 5-(4-chlorophenyl)-1-methyl-1H-imidazole-2-thiol. 1H NMR (300 MHz, CDCl3) δ 7.41-7.25 (m, 5H), 3.62 (s, 2H), 3.49 (s, 3H), 3.46 (s, 2H), 2.04-1.63 (m, 6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07282512B2
Source datasetuspto-grants-2007_10
ORD IDord-18b55d116dde4613af199cb523e17255
Source noteuspto-grants-2007_10