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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1180899Generated: October 31, 2026

Ethyl isocyanate → N-ethyl-N'-[4-(2-methyl-5-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1,3-thiazol-4-yl)phenyl]urea

https://huagongshe.com/reaction/1180899

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl isocyanateHCID 8022—
Reactant4-(2-methyl-5-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1,3-thiazol-4-yl)anilineHCID 68996042—
ProductN-ethyl-N'-[4-(2-methyl-5-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1,3-thiazol-4-yl)phenyl]ureaHCID 68995209—

Reaction Steps

Following the procedure described in Example 1 with 4-(2-methyl-5-{1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-4-yl}-1,3-thiazol-4-yl)aniline and ethyl isocyanate provided the title product. ESMS [M+H]+: 532.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07282588B2
Source datasetuspto-grants-2007_10
ORD IDord-e759b741f57545419950efa0cf64e68e
Source noteuspto-grants-2007_10