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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1180906Generated: October 25, 2026

4-Bromo-6-chloro-1H-pyrrolo[2,3-b]pyridine → 6-chloro-4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine

https://huagongshe.com/reaction/1180906

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-6-chloro-1H-pyrrolo[2,3-b]pyridineHCID 24729595—
Reactant1-ethyl-3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 68995348—
Product6-chloro-4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridineHCID 86613321—

Reaction Steps

Following the procedure described for Intermediate 6 with 4-bromo-6-chloro-1H-pyrrolo[2,3-b]pyridine and 1-ethyl-3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole afforded the title compound. ESMS [M+H]+: 368.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07282588B2
Source datasetuspto-grants-2007_10
ORD IDord-03c483d253b24208a7f76d3f41bd6f3d
Source noteuspto-grants-2007_10