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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1180907Generated: October 25, 2026

1-ethyl-3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole → 4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid

https://huagongshe.com/reaction/1180907

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-ethyl-3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazoleHCID 68995348—
Reactantethyl 4-bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acidHCID 68997770—
Product4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acidHCID 46236484—

Reaction Steps

Following the procedure described for Intermediate 6 with ethyl 4-bromo-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid and 1-ethyl-3-(4-nitrophenyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole provided title compound. ESMS [M+H]+: 378.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07282588B2
Source datasetuspto-grants-2007_10
ORD IDord-f574b5e091eb4414a0e2dacaeef4b597
Source noteuspto-grants-2007_10