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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1180936Generated: October 31, 2026

2-(Ethylamino)ethanol → 2-(ethyl {[4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]methyl}amino)ethanol

https://huagongshe.com/reaction/1180936

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Ethylamino)ethanolHCID 8072—
Reactant4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carbaldehydeHCID 86613327—
Product2-(ethyl {[4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]methyl}amino)ethanolHCID 69000627—

Reaction Steps

Following the procedure described in Intermediate 101 using 4-[1-ethyl-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-carbaldehyde and 2-(ethylamino)ethanol provided the title compound as a yellow solid. ESMS [M+H]+: 651.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07282588B2
Source datasetuspto-grants-2007_10
ORD IDord-ab947dd45e0f4ee6b362fe262b515585
Source noteuspto-grants-2007_10