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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1180951Generated: October 31, 2026

2-(Ethylamino)ethanol → 2-[ethyl({4-[4-[1-(1-methylethyl)-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-indol-2-yl]phenyl}methyl)amino]ethanol

https://huagongshe.com/reaction/1180951

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Ethylamino)ethanolHCID 8072—
Reactant4-[4-[1-(1-methylethyl)-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-indol-2-yl]benzaldehydeHCID 86613326—
Product2-[ethyl({4-[4-[1-(1-methylethyl)-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-indol-2-yl]phenyl}methyl)amino]ethanolHCID 68998220—

Reaction Steps

Following the procedure described for Intermediate 101 using 4-[4-[1-(1-methylethyl)-3-(4-nitrophenyl)-1H-pyrazol-4-yl]-1-(phenylsulfonyl)-1H-indol-2-yl]benzaldehyde and 2-(ethylamino)ethanol (18.8 mmol) provided the title compound. ESMS [M+H]+: 665.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07282588B2
Source datasetuspto-grants-2007_10
ORD IDord-36ac36f4d874409ba547dacb47a9c07e
Source noteuspto-grants-2007_10