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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1180969Generated: October 25, 2026

L-Alanine 1,1-dimethylethyl ester → tert-Butyl(2S)-2-(3-azido-2-oxopyrrolidin-1-yl)propanoate

https://huagongshe.com/reaction/1180969

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-Alanine 1,1-dimethylethyl esterHCID 89016—
ReactantEthyl 2-azido-4-iodobutanoateHCID 22017145—
Producttert-Butyl(2S)-2-(3-azido-2-oxopyrrolidin-1-yl)propanoateHCID 86593859—

Reaction Steps

Using ethyl 2-azido-4-iodobutanoate and L-alanine tert-butyl ester, and the procedure described for Intermediate 33, the title compound was prepared as a mixture of two diastereoisomers.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07282497B2
Source datasetuspto-grants-2007_10
ORD IDord-387a547c4414482cb0bdd1843ef7fbc8
Source noteuspto-grants-2007_10