HRID1181078

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1ccc(S(=O)(=O)OCCc2nc(-c3ccc(-c4ccccc4)cc3)oc2C)cc1

HCID12966835

未命名化合物

HCID58978962

未命名化合物

PRODUCTS

生成物

结构：COC(=O)CCc1ccc(OCCc2nc(-c3ccc(-c4ccccc4)cc3)oc2C)cc1CNC(=O)OC(C)C

HCID58979254

未命名化合物

PROCEDURE

实验过程

3-[4-Hydroxy-2-(isopropoxycarbonylamino-methyl)-phenyl]-propionic acid methyl ester (Preparation 17) and toluene-4-sulfonic acid 2-(2-biphenyl-4-yl-5-methyl-oxazol-4-yl)ethyl ester (Preparation 1) were combined according to Standard procedure A to give the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-276074cc22604498bec28e7a14e99460
来源数据集: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07282501B2
来源说明: uspto-grants-2007_10

反应 SMILES

[CH3:1][O:2][C:3](=[O:21])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][C:7]=1[CH2:13][NH:14][C:15]([O:17][CH:18]([CH3:20])[CH3:19])=[O:16].[C:22]1([C:47]2[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=2)[CH:27]=[CH:26][C:25]([C:28]2[O:29][C:30]([CH3:46])=[C:31]([CH2:33][CH2:34]OS(C3C=CC(C)=CC=3)(=O)=O)[N:32]=2)=[CH:24][CH:23]=1>>[CH3:1][O:2][C:3](=[O:21])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:34][CH2:33][C:31]2[N:32]=[C:28]([C:25]3[CH:26]=[CH:27][C:22]([C:47]4[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=4)=[CH:23][CH:24]=3)[O:29][C:30]=2[CH3:46])=[CH:8][C:7]=1[CH2:13][NH:14][C:15]([O:17][CH:18]([CH3:19])[CH3:20])=[O:16]