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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181095Generated: November 2, 2026

Trifluoroacetic acid → HCID 58979224, compound

https://huagongshe.com/reaction/1181095

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 69231842HCID 69231842—
SolventDichloromethaneHCID 6344—
ProductHCID 58979224HCID 58979224133.7%

Reaction Steps

A solution of 2-{2-(tert-butoxycarbonylamino-methyl)-4-[2-(5-methyl-2-phenyl-oxazol-4-yl)-ethoxy]-phenoxy}-2-methyl-propionic acid ethyl ester (350 mg, 0.650 mmol) in CH2Cl2 (10 mL) was treated at ambient temperature with TFA (4 mL) and stirred for 2.5 h. The solution was concentrated and co-evaporated with CCl4 (3×) to yield the title compound as a foam (381 mg, quantitative).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07282501B2
Source datasetuspto-grants-2007_10
ORD IDord-9912f855235042d59dfb07139c118ba0
Source noteuspto-grants-2007_10