Phenyl chloroformate → HCID 11774079, compound

HRID 1181187Notes

Reaction equation

HRID 1181187 reaction equation
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH2:12])[S:11][C:7]=2[C:6]([N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:5][CH:4]=1.Cl[C:20](OC1C=CC=CC=1)=[O:21].[CH:29]12[O:36][CH:33]([CH2:34][CH2:35]1)[CH2:32][NH:31][CH2:30]2>>[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:20]([N:31]3[CH2:30][CH:29]4[O:36][CH:33]([CH2:34][CH2:35]4)[CH2:32]3)=[O:21])[S:11][C:7]=2[C:6]([N:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:5][CH:4]=1

Participants

4

Reactant 3

HCID 15891Phenyl chloroformateHCID 114028614-Methoxy-7-morpholinobenzo[d]thiazol-2-amineHCID 120692318-Oxa-3-azabicyclo[3.2.1]octane

Product 1

HCID 11774079HCID 11774079, compound

Procedure

Using 4-methoxy-7-morpholin-4-yl-benzothiazol-2-ylamine, phenyl chloroformate and 8-oxa-3-aza-bicyclo[3.2.1]octane, the title compound was prepared as white crystals (67% yield), mp 229-231° C. MS: m/e=405(M+H+).

Sources & evidence

ORD record
ord-21fd09a7ae244987a132f343848569a1
Source dataset
uspto-grants-2007_10
Patent number
US07285548B2

Reaction notes

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