反应详情

A solution of N9-benzyladenine (1 mmol) in acetic acid buffer (pH=4) was treated with bromine (1 mmol) at room temperature for 12 h. The reaction was quenched with 10% sodium sulfite solution and extracted with dichloromethane. The combined extracts were dried (Na2SO4) and evaporated to dryness. Chromatography afforded N9-benzyl-8-bromoadenine.

1. customThe reaction was quenched with 10% sodium sulfite solution
2. extractionextracted with dichloromethane
3. dry with materialThe combined extracts were dried (Na2SO4)
4. customevaporated to dryness