HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus tribromide → N9-phenethyl-8-bromomethyladenine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus tribromide | HCID 24614 | — |
| Reactant | N9-phenethyl-8-hydroxymethyladenine | HCID 42637018 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N9-phenethyl-8-bromomethyladenine | HCID 42637845 | — |
Reaction Steps
A solution of N9-phenethyl-8-hydroxymethyladenine (1 mmol) in methylene chloride was treated with phosphorus tribromide (1 mmol) at 25° C. for 1 h. Extraction and chromatography gave N9phenethyl-8-bromomethyl-adenine as a white solid. TLC: Rf=0.31, 10% MeOH—CH2Cl2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07285543B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-230207b0987b46ac9eae92b8f3039d9d |
| Source note | uspto-grants-2007_10 |