Methanimidamide, hydrochloride (1:1) → HCID 178418891, compound

HRID 1181246Notes

Reaction equation

HRID 1181246 reaction equation
C[O:2][C:3](=O)[CH:4]([O:9][C:10]1[CH:15]=[C:14]([O:16][CH3:17])[CH:13]=[CH:12][C:11]=1[Cl:18])[C:5](OC)=[O:6].Cl.[CH:21]([NH2:23])=[NH:22]>>[Cl:18][C:11]1[CH:12]=[CH:13][C:14]([O:16][CH3:17])=[CH:15][C:10]=1[O:9][C:4]1[C:5]([OH:6])=[N:22][CH:21]=[N:23][C:3]=1[OH:2]

Participants

3

Reactant 2

HCID 10313058Methanimidamide, hydrochloride (1:1)HCID 21803835Dimethyl (2-chloro-5-methoxy-phenoxy)malonate

Product 1

HCID 178418891HCID 178418891, compound

Procedure

5-(2-Chloro-5-methoxy-phenoxy)-pyrimidine-4,6-diol was prepared from 2-(2-chloro-5-methoxy-phenoxy)-malonic acid dimethyl ester and formamidine hydrochloride according to the procedure described in Referential Example 1c.

Sources & evidence

ORD record
ord-3145196866684d2c9aaab64826c61e23
Source dataset
uspto-grants-2007_10
Patent number
US07285549B2

Reaction notes

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