Dimethylamine → HCID 58980839, compound

HRID 1181370Notes

Reaction equation

Br[CH2:2][CH2:3][CH2:4][N:5]([C:16]1[CH:21]=[CH:20][C:19]([N:22]2[C:27](=[O:28])[C:26]3[S:29][C:30]([C:32]4[CH:37]=[CH:36][C:35]([Cl:38])=[CH:34][CH:33]=4)=[CH:31][C:25]=3[N:24]=[CH:23]2)=[CH:18][C:17]=1[O:39][CH3:40])[S:6]([C:9]1[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=1)(=[O:8])=[O:7].[CH3:41][NH:42][CH3:43]>>[Cl:38][C:35]1[CH:36]=[CH:37][C:32]([C:30]2[S:29][C:26]3[C:27](=[O:28])[N:22]([C:19]4[CH:20]=[CH:21][C:16]([N:5]([CH2:4][CH2:3][CH2:2][N:42]([CH3:43])[CH3:41])[S:6]([C:9]5[CH:14]=[CH:13][C:12]([CH3:15])=[CH:11][CH:10]=5)(=[O:8])=[O:7])=[C:17]([O:39][CH3:40])[CH:18]=4)[CH:23]=[N:24][C:25]=3[CH:31]=2)=[CH:33][CH:34]=1

Participants

Reactant 2

HCID 674Dimethylamine

HCID 58980877HCID 58980877, compound

Product 1

HCID 58980839HCID 58980839, compound

Procedure

The title compound was prepared by reaction of N-(3-bromopropyl)-N{4-[6-(4-chlorophenyl)4-oxothieno[3,2-d]pyrimidin-3(4H)-yl]-2-methoxyphenyl}4-methylbenzenesulfonamide (the title compound from Example K15) and dimethylamine. LCMS m/z 623 (MH+).

Sources & evidence

ORD record: ord-75fed1bfd2db4bc1bcb46c2075bc1379
Source dataset: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07285557B2

Reaction notes

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