3-Methylisoquinolin-5-amine → HCID 10317324, compound

HRID 1181453Notes

Reaction equation

HRID 1181453 reaction equation
[CH3:1][C:2]1[N:3]=[CH:4][C:5]2[CH:6]=[CH:7][CH:8]=[C:9]([NH2:12])[C:10]=2[CH:11]=1.[F:13][C:14]([F:27])([F:26])[O:15][C:16]1[CH:25]=[CH:24][C:19]([CH2:20][N:21]=[C:22]=[O:23])=[CH:18][CH:17]=1>>[CH3:1][C:2]1[N:3]=[CH:4][C:5]2[C:10]([CH:11]=1)=[C:9]([NH:12][C:22]([NH:21][CH2:20][C:19]1[CH:18]=[CH:17][C:16]([O:15][C:14]([F:13])([F:27])[F:26])=[CH:25][CH:24]=1)=[O:23])[CH:8]=[CH:7][CH:6]=2

Participants

3

Reactant 2

HCID 122120553-Methylisoquinolin-5-amineHCID 156751741-(Isocyanatomethyl)-4-(trifluoromethoxy)benzene

Product 1

HCID 10317324HCID 10317324, compound

Procedure

Prepared from 3-methylisoquinolin-5-amine (Description 45) and [4-(trifluoromethoxy)benzyl]isocyanate (Description 59) according to the procedure of Description 61. m/z (ES+) 376 (M+H)+.

Sources & evidence

ORD record
ord-e28a92f9cd0a4fb0b753185b17e96851
Source dataset
uspto-grants-2007_10
Patent number
US07285563B2

Reaction notes

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