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HRID1181454

反应详情

EQUATION

反应方程式

HRID 1181454 的结构方程式

REACTANTS

反应物

3
结构：Cc1cc2c([N+](=O)[O-])cccc2cn1
HCID274973

3-methyl-5-nitroisoquinoline

C10H8N2O2

结构：Cc1cc2cccc([N+](=O)[O-])c2cn1
HCID21567172

未命名化合物

结构：O=C=NCc1ccc(C(F)(F)F)cc1
HCID22337699

1-(Isocyanatomethyl)-4-(trifluoromethyl)benzene

C9H6F3NO

PRODUCTS

生成物

1
结构：Cc1cc2cccc(NC(=O)NCc3ccc(C(F)(F)F)cc3)c2cn1
HCID69522806

未命名化合物

PROCEDURE

实验过程

A sample of 3-methyl-5-nitroisoquinoline (Description 44) enriched in the nitration byproduct 3-methyl-8-nitroisoquinoline was reduced according to Description 45 and the mixture of amines reacted with [4-(trifluoromethyl)benzyl]isocyanate (Description 58) according to the procedure of Description 61. Isomer separation of the products gave the title compound. m/z (ES+) 360 (M+H)+.

WORKUP

后处理

  1. customIsomer separation of the products