4-(Trifluoromethyl)benzyl isocyanate → HCID 86598041, compound

HRID 1181459Notes

Reaction equation

HRID 1181459 reaction equation
[Cl:1][C:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[C:7]([NH2:12])[C:6]=2[CH:5]=[C:4]([CH2:13][CH3:14])[N:3]=1.[F:15][C:16]([F:28])([F:27])[C:17]1[CH:26]=[CH:25][C:20]([CH2:21][N:22]=[C:23]=[O:24])=[CH:19][CH:18]=1>>[Cl:1][C:2]1[C:11]2[C:6](=[C:7]([NH:12][C:23]([NH:22][CH2:21][C:20]3[CH:19]=[CH:18][C:17]([C:16]([F:15])([F:28])[F:27])=[CH:26][CH:25]=3)=[O:24])[CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([CH2:13][CH3:14])[N:3]=1

Participants

3

Reactant 2

HCID 223376994-(Trifluoromethyl)benzyl isocyanateHCID 86598042HCID 86598042, compound

Product 1

HCID 86598041HCID 86598041, compound

Procedure

Prepared from 1-chloro-3-ethylisoquinolin-5-amine (Description 66) and [4-(trifluoromethyl)benzyl]isocyanate (Description 58) according to the procedure of Description 61. m/z (ES+) 408, 410 (M+H)+.

Sources & evidence

ORD record
ord-8a7e802368374d99b6fdcbda219f2fe1
Source dataset
uspto-grants-2007_10
Patent number
US07285563B2

Reaction notes

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