6-Aminoquinoline → N-(4-phenoxyphenyl)-N'-[quinolin-6-yl]urea

HRID 1181464Notes

Reaction equation

HRID 1181464 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[CH:5]2.[O:12]([C:19]1[CH:24]=[CH:23][C:22]([N:25]=[C:26]=[O:27])=[CH:21][CH:20]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[O:12]([C:19]1[CH:20]=[CH:21][C:22]([NH:25][C:26]([NH:1][C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[N:8]=[CH:7][CH:6]=[CH:5]3)=[O:27])=[CH:23][CH:24]=1)[C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 113736-AminoquinolineHCID 27348964-Phenoxyphenyl isocyanate

Product 1

HCID 69522209N-(4-phenoxyphenyl)-N'-[quinolin-6-yl]urea

Procedure

Prepared from 6-aminoquinoline and 4-phenoxyphenyl isocyanate. m/z (ES+) 356 (M+H)+.

Sources & evidence

ORD record
ord-bb5d3d8dd1de488b8fd95c9d62503a90
Source dataset
uspto-grants-2007_10
Patent number
US07285563B2

Reaction notes

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