4-(Trifluoromethyl)benzyl isocyanate → HCID 69522683, compound

HRID 1181476Notes

Reaction equation

HRID 1181476 reaction equation
[F:1][C:2]1[CH:11]=[C:10]([F:12])[C:9]2[CH:8]=[N:7][C:6]([CH3:13])=[CH:5][C:4]=2[C:3]=1[NH2:14].[F:15][C:16]([F:28])([F:27])[C:17]1[CH:26]=[CH:25][C:20]([CH2:21][N:22]=[C:23]=[O:24])=[CH:19][CH:18]=1>>[F:1][C:2]1[C:3]([NH:14][C:23]([NH:22][CH2:21][C:20]2[CH:19]=[CH:18][C:17]([C:16]([F:15])([F:28])[F:27])=[CH:26][CH:25]=2)=[O:24])=[C:4]2[C:9](=[C:10]([F:12])[CH:11]=1)[CH:8]=[N:7][C:6]([CH3:13])=[CH:5]2

Participants

3

Reactant 2

HCID 223376994-(Trifluoromethyl)benzyl isocyanateHCID 69158066HCID 69158066, compound

Product 1

HCID 69522683HCID 69522683, compound

Procedure

Prepared from 6,8-difluoro-3-methylisoquinolin-5-amine (Description 73) and [4-(trifluoromethyl)benzyl]isocyanate (Description 58) according to Description 61. m/z (ES+) 396 (M+H)+.

Sources & evidence

ORD record
ord-568490681e4d4c009a8f2335c168a7eb
Source dataset
uspto-grants-2007_10
Patent number
US07285563B2

Reaction notes

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