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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181484Generated: October 26, 2026

4-(Trifluoromethyl)benzyl isocyanate → N-(7-Chloroisoquinolin-5-yl)-N'-[4-(trifluoromethyl)benzyl]urea

https://huagongshe.com/reaction/1181484

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)benzyl isocyanateHCID 22337699—
Reactant7-Chloroisoquinolin-5-amineHCID 44558546—
ProductN-(7-Chloroisoquinolin-5-yl)-N'-[4-(trifluoromethyl)benzyl]ureaHCID 69523243—

Reaction Steps

Prepared from 7-chloroisoquinolin-5-amine (Description 87) and [4-(trifluoromethyl)benzyl]isocyanate (Description 58) according to Description 61. m/z (ES+) 380 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285563B2
Source datasetuspto-grants-2007_10
ORD IDord-d8a795c4e56946158c35c71eac3ca39c
Source noteuspto-grants-2007_10