1-(Isocyanatomethyl)-4-(trifluoromethoxy)benzene → HCID 69523273, compound

HRID 1181486Notes

Reaction equation

HRID 1181486 reaction equation
[F:1][C:2]1[CH:11]=[CH:10][C:9]2[CH:8]=[N:7][CH:6]=[CH:5][C:4]=2[C:3]=1[NH2:12].[F:13][C:14]([F:27])([F:26])[O:15][C:16]1[CH:25]=[CH:24][C:19]([CH2:20][N:21]=[C:22]=[O:23])=[CH:18][CH:17]=1>>[F:1][C:2]1[C:3]([NH:12][C:22]([NH:21][CH2:20][C:19]2[CH:18]=[CH:17][C:16]([O:15][C:14]([F:13])([F:27])[F:26])=[CH:25][CH:24]=2)=[O:23])=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[N:7][CH:6]=[CH:5]2

Participants

3

Reactant 2

HCID 156751741-(Isocyanatomethyl)-4-(trifluoromethoxy)benzeneHCID 450907626-Fluoroisoquinolin-5-amine

Product 1

HCID 69523273HCID 69523273, compound

Procedure

Prepared from 6-fluoroisoquinolin-5-amine (Description 89) and [4-(trifluoromethoxy)benzyl]isocyanate (Description 59) according to Description 61. m/z (ES+) 394 (M+H)+.

Sources & evidence

ORD record
ord-1611d2b8f11047f5813919e181144b5d
Source dataset
uspto-grants-2007_10
Patent number
US07285563B2

Reaction notes

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