4-(Trifluoromethyl)benzyl isocyanate → HCID 69522762, compound

HRID 1181493Notes

Reaction equation

HRID 1181493 reaction equation
[F:1][C:2]1[CH:11]=[CH:10][C:9]2[C:8]([CH3:12])=[N:7][CH:6]=[CH:5][C:4]=2[C:3]=1[NH2:13].[F:14][C:15]([F:27])([F:26])[C:16]1[CH:25]=[CH:24][C:19]([CH2:20][N:21]=[C:22]=[O:23])=[CH:18][CH:17]=1>>[F:1][C:2]1[C:3]([NH:13][C:22]([NH:21][CH2:20][C:19]2[CH:18]=[CH:17][C:16]([C:15]([F:14])([F:27])[F:26])=[CH:25][CH:24]=2)=[O:23])=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8]([CH3:12])=[N:7][CH:6]=[CH:5]2

Participants

3

Reactant 2

HCID 223376994-(Trifluoromethyl)benzyl isocyanateHCID 69522020HCID 69522020, compound

Product 1

HCID 69522762HCID 69522762, compound

Procedure

Prepared from 6-fluoro-1-methylisoquinolin-5-amine (Description 103) and [4-(trifluoromethyl)benzyl]isocyanate (description 58) according to the procedure of description 61. m/z (ES+) 378 (M+H)+.

Sources & evidence

ORD record
ord-070e633712b64b40889c6aea2f0aad0f
Source dataset
uspto-grants-2007_10
Patent number
US07285563B2

Reaction notes

Loading…