Methyl 5-aminoisoquinoline-3-carboxylate → HCID 69522620, compound

HRID 1181498Notes

Reaction equation

HRID 1181498 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[C:5]([C:12]([O:14][CH3:15])=[O:13])[N:6]=[CH:7]2.[F:16][C:17]([F:29])([F:28])[C:18]1[CH:27]=[CH:26][C:21]([CH2:22][N:23]=[C:24]=[O:25])=[CH:20][CH:19]=1>>[CH3:15][O:14][C:12]([C:5]1[N:6]=[CH:7][C:8]2[C:3]([CH:4]=1)=[C:2]([NH:1][C:24]([NH:23][CH2:22][C:21]1[CH:20]=[CH:19][C:18]([C:17]([F:16])([F:29])[F:28])=[CH:27][CH:26]=1)=[O:25])[CH:11]=[CH:10][CH:9]=2)=[O:13]

Participants

3

Reactant 2

HCID 22032628Methyl 5-aminoisoquinoline-3-carboxylateHCID 223376994-(Trifluoromethyl)benzyl isocyanate

Product 1

HCID 69522620HCID 69522620, compound

Procedure

Prepared from methyl 5-aminoisoquinoline-3-carboxylate (Description 107) and [4-(trifluoromethyl)benzyl]isocyanate (Description 58) according to Description 61. m/z (ES+) 404 (M+H)+.

Sources & evidence

ORD record
ord-2606d8038af9426ca82fac17decad846
Source dataset
uspto-grants-2007_10
Patent number
US07285563B2

Reaction notes

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