6-Amino-1-ethyl-3,3-dimethyl-5-nitro-1,3-dihydro-indol-2-one → 5,6-Diamino-1-ethyl-3,3-dimethyl-1,3-dihydro-indol-2-one

Participants

Reaction Steps

To a solution of 6-amino-1-ethyl-3,3-dimethyl-5-nitro-1,3-dihydro-indol-2-one (4.15 g, 16.65 mmol) in ethanol (80 ml) PtO2 (0.4 g) was added and the mixture hydrogenated at room temperature for 3.5 h. After filtration and evaporation of the solvents 3.25 g (89%) 5,6-diamino-1-ethyl-3,3-dimethyl-1,3-dihydro-indol-2-one was isolated as orange solid.

Provenance & Evidence