HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → ethyl-2-(2,4-dimethoxyphenyl)-4,5-dihydro-thiazole-4-(R)-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethyl L-cysteinate | HCID 13359 | — |
| Reactant | 2,4-Dimethoxybenzonitrile | HCID 77750 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | ethyl-2-(2,4-dimethoxyphenyl)-4,5-dihydro-thiazole-4-(R)-carboxylate | HCID 17747724 | — |
Reaction Steps
2,4-Dimethoxybenzonitrile, (R)-cysteine ethyl ester and about 5 equivalents of triethylamine are refluxed in ethanol for about 6-8 hours to obtain ethyl-2-(2,4-dimethoxyphenyl)-4,5-dihydro-thiazole-4-(R)-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07285670B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-3378e4c7f0274d529dac8e8573c59c40 |
| Source note | uspto-grants-2007_10 |