HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181645Generated: October 25, 2026
Pentyltriphenylphosphonium bromide → (Butylmethylene)triphenylphosphorane
https://huagongshe.com/reaction/1181645
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pentyltriphenylphosphonium bromide | HCID 2724565 | — |
| Reactant | Potassium bis(trimethylsilyl)amide | HCID 3251421 | — |
| Reactant | 1-(3,5-Dimethoxyphenyl)-1-(hex-1-enyl)-cyclopentane | HCID 69204664 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (Butylmethylene)triphenylphosphorane | HCID 10980496 | — |
Reaction Steps
To a suspension of pentyltriphenylphosphonium bromide (5 equiv.) in dry THF (0.18M) at 0° C., under an argon atmosphere was added potassium bis(trimethylsilyl) amide (4.9 equiv.). The mixture was warmed to 10° C. and stirred for an additional 30 min to ensure complete formation of the orange ylide. The resulting slurry was used in the preparation of 1-(3,5-dimethoxyphenyl)-1-(hex-1-enyl)-cyclopentane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07285683B2 |
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| Source dataset | uspto-grants-2007_10 |
|---|
| ORD ID | ord-5608aedb77d3428e9e4779505b624f9e |
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| Source note | uspto-grants-2007_10 |
|---|
