Hydrazine hydrate (1:1) → 6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedione

Participants

Reaction Steps

Hydrazine hydrate (6.5 ml) was added to a solution of 6-Chloro-1-isobutyl-3-methylpyrmidine-2,4(1H,3H)-dione (10 g) in ethanol (40 ml). The mixture was heated at reflux for 5 hours, cooled to room temperature and then evaporated under reduced pressure. The residue was crystallized from ethanol to give the subtitle compound (6.7 g). Mass: 213.00 (M+H).

Provenance & Evidence