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HRID 1181680作成日：2026年10月25日
Triethylamine → 3-[5-methyl-2-(1-naphthylmethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]benzoic acid
https://huagongshe.com/reaction/1181680
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | 3-Carboxybenzaldehyde | HCID 12077 | — |
| 反応物 | 1-Naphthaldehyde (1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)hydrazone | HCID 69845528 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 3-[5-methyl-2-(1-naphthylmethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]benzoic acid | HCID 136334115 | — |
反応手順
1-naphthaldehyde (1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)hydrazone (2.12 g) and triethylamine (0.8 ml) was added to a suspension of Resin bound 3-formylbenzoic acid in dimethylformamide (15 ml), and the mixture was shaken at 90° C. for 16 hours. The resin was filtered and washed (3 times) DMF, CH2Cl2, MeOH, CH2Cl2, and dried in vacuum to give the subtitle compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US07285558B2 |
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| 出典データセット | uspto-grants-2007_10 |
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| ORD ID | ord-d0dd19257cd84a4faa51d8b762041751 |
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| 出典メモ | uspto-grants-2007_10 |
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