Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181691Generated: November 2, 2026

5-Bromoindole-3-carbaldehyde → methyl 5-{2-[(5-bromo-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylate

https://huagongshe.com/reaction/1181691

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromoindole-3-carbaldehydeHCID 70137—
Reactantmethyl 5-formyl-1-methyl-1H-pyrrole-3-carboxylateHCID 14173855—
Reactant6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedioneHCID 19356084—
Productmethyl 5-{2-[(5-bromo-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylateHCID 58981021—

Reaction Steps

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 5-bromo-1H-indole-3-carbaldehyde, followed by methyl 5-formyl-1-methyl-1H-pyrrole-3-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285558B2
Source datasetuspto-grants-2007_10
ORD IDord-0807be7322b14691997896690f0f001b
Source noteuspto-grants-2007_10