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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181698Generated: October 26, 2026

3-Formyl-1H-indole-5-carbonitrile → methyl 5-{2-[(5-cyano-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylate

https://huagongshe.com/reaction/1181698

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Formyl-1H-indole-5-carbonitrileHCID 28504—
Reactantmethyl 5-formyl-1-methyl-1H-pyrrole-3-carboxylateHCID 14173855—
Reactant6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedioneHCID 19356084—
Productmethyl 5-{2-[(5-cyano-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylateHCID 58981032—

Reaction Steps

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 3-formyl-1H-indole-5-carbonitrile, followed by methyl 5-formyl-1-methyl-1H-pyrrole-3-carboxylate. Mass: 514.05 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285558B2
Source datasetuspto-grants-2007_10
ORD IDord-89b5d99073b54ef29d8e7af30a8a63f2
Source noteuspto-grants-2007_10