Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181699Generated: October 27, 2026

5-ethyl-1H-indole-3-carbaldehyde → methyl 5-{7-(cyclopropylmethyl)-2-[(5-ethyl-1H-indol-3-yl)methyl]-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl)-1-methyl-1H-pyrrole-3-carboxylate

https://huagongshe.com/reaction/1181699

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-ethyl-1H-indole-3-carbaldehydeHCID 12399211—
Reactantmethyl 5-formyl-1-methyl-1H-pyrrole-3-carboxylateHCID 14173855—
Reactant1-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dioneHCID 69427171—
Productmethyl 5-{7-(cyclopropylmethyl)-2-[(5-ethyl-1H-indol-3-yl)methyl]-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl)-1-methyl-1H-pyrrole-3-carboxylateHCID 58980912—

Reaction Steps

This compound was made following the procedure described above, starting with 1-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 5-ethyl-1H-indole-3-carbaldehyde, followed by methyl 5-formyl-1-methyl-1H-pyrrole-3-carboxylate. Mass: 515.25 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285558B2
Source datasetuspto-grants-2007_10
ORD IDord-a0017ff5494d4e068038118b245f39b1
Source noteuspto-grants-2007_10