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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181701Generated: October 27, 2026

5-Bromoindole-3-carbaldehyde → 5-{2-[(5-bromo-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl)-1-methyl-1H-pyrrole-3-carboxylic acid

https://huagongshe.com/reaction/1181701

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromoindole-3-carbaldehydeHCID 70137—
Reactant6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedioneHCID 19356084—
Reactant5-formyl-1-methyl-1H-pyrrole-3-carboxylic acidHCID 45083779—
Product5-{2-[(5-bromo-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl)-1-methyl-1H-pyrrole-3-carboxylic acidHCID 58981159—

Reaction Steps

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 5-bromo-1H-indole-3-carbaldehyde, followed by 5-formyl-1-methyl-1H-pyrrole-3-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285558B2
Source datasetuspto-grants-2007_10
ORD IDord-0c762e69cf5348fd82364138d09cb2c6
Source noteuspto-grants-2007_10