HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl cyanophosphonate → 5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-N-(pyridin-4-ylmethyl)-1H-pyrrole-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl cyanophosphonate | HCID 76257 | — |
| Reactant | 4-(Methylamino)pyridine | HCID 123098 | — |
| Reactant | 5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylic acid | HCID 58981063 | — |
| Product | 5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-N-(pyridin-4-ylmethyl)-1H-pyrrole-3-carboxamide | HCID 58981047 | — |
Reaction Steps
This compound was synthesized by the reaction of 5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylic acid and pyridin-4-yl-methylamine using diethyl cyanophosphonate as a coupling reagent. Mass: 599.15 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07285558B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-15a29db017b643588d370abb3997a45c |
| Source note | uspto-grants-2007_10 |