HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine → 2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-3-[1-methyl-4-(piperazin-1-ylcarbonyl)-1H-pyrrol-2-yl]-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | Diethyl cyanophosphonate | HCID 76257 | — |
| Reactant | 5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylic acid | HCID 58981063 | — |
| Product | 2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-3-[1-methyl-4-(piperazin-1-ylcarbonyl)-1H-pyrrol-2-yl]-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione | HCID 58981169 | — |
Reaction Steps
This compound was synthesized by the reaction of 5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylic acid and piperazine using diethyl cyanophosphonate as a coupling reagent Mass: 577.17 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07285558B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-c5f131da0e284922bd2150885c228369 |
| Source note | uspto-grants-2007_10 |