5-chloro-1H-indole-3-carbaldehyde → HCID 58980934, compound

HRID 1181744Notes

Reaction equation

HRID 1181744 reaction equation
[CH:1]1([CH2:4][N:5]2[C:10]([NH:11][NH2:12])=[CH:9][C:8](=[O:13])[N:7]([CH3:14])[C:6]2=[O:15])[CH2:3][CH2:2]1.[Cl:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH:21]=[C:20]2[CH:26]=O.[C:28]([C:31]1[CH:32]=[C:33]([CH:37]=O)[N:34]([CH3:36])[CH:35]=1)(=[O:30])[CH3:29]>>[C:28]([C:31]1[CH:32]=[C:33]([C:37]2[N:12]([CH2:26][C:20]3[C:19]4[C:23](=[CH:24][CH:25]=[C:17]([Cl:16])[CH:18]=4)[NH:22][CH:21]=3)[N:11]=[C:10]3[C:9]=2[C:8](=[O:13])[N:7]([CH3:14])[C:6](=[O:15])[N:5]3[CH2:4][CH:1]2[CH2:2][CH2:3]2)[N:34]([CH3:36])[CH:35]=1)(=[O:30])[CH3:29]

Participants

4

Reactant 3

HCID 27953745-chloro-1H-indole-3-carbaldehydeHCID 126762684-Acetyl-1-methyl-1H-pyrrole-2-carbaldehydeHCID 694271711-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione

Product 1

HCID 58980934HCID 58980934, compound

Procedure

This compound was made following the procedure described above, starting with 1-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 5-chloro-1H-indole-3-carbaldehyde, followed by 4-acetyl-1-methyl-1H-pyrrole-2-carbaldehyde. Mass: 505.12 (M+H).

Sources & evidence

ORD record
ord-35422f35d12b43be956a54d9ab3d6a63
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

Loading…