5-chloro-1H-indole-3-carbaldehyde → HCID 58980979, compound

HRID 1181746Notes

Reaction equation

HRID 1181746 reaction equation
[CH:1]1([CH2:4][N:5]2[C:10]([NH:11][NH2:12])=[CH:9][C:8](=[O:13])[N:7]([CH3:14])[C:6]2=[O:15])[CH2:3][CH2:2]1.[Cl:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH:21]=[C:20]2[CH:26]=O.[CH3:28][N:29]1[CH:33]=[C:32]([C:34](=[O:39])[C:35]([F:38])([F:37])[F:36])[CH:31]=[C:30]1[CH:40]=O>>[Cl:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH:21]=[C:20]2[CH2:26][N:12]1[C:40]([C:30]2[N:29]([CH3:28])[CH:33]=[C:32]([C:34](=[O:39])[C:35]([F:37])([F:36])[F:38])[CH:31]=2)=[C:9]2[C:10]([N:5]([CH2:4][CH:1]3[CH2:2][CH2:3]3)[C:6](=[O:15])[N:7]([CH3:14])[C:8]2=[O:13])=[N:11]1

Participants

4

Reactant 3

HCID 27953745-chloro-1H-indole-3-carbaldehydeHCID 450809851-Methyl-4-(trifluoroacetyl)-1H-pyrrole-2-carbaldehydeHCID 694271711-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione

Product 1

HCID 58980979HCID 58980979, compound

Procedure

This compound was made following the procedure described above, starting with 1-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 5-chloro-1H-indole-3-carbaldehyde, followed by 1-methyl-4-(trifluoroacetyl)-1H-pyrrole-2-carbaldehyde. Mass: 559.15 (M+H).

Sources & evidence

ORD record
ord-7df9e51aa1394aeab0936810a660b693
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

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