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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181749Generated: October 25, 2026

1-Methyl-2-imidazolecarboxaldehyde → 7-isobutyl-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2-[(5-nitro-1H-indol-3-yl)methyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

https://huagongshe.com/reaction/1181749

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-2-imidazolecarboxaldehydeHCID 139575—
Reactant5-nitro-1H-indole-3-carbaldehydeHCID 246039—
Reactant6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedioneHCID 19356084—
Product7-isobutyl-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2-[(5-nitro-1H-indol-3-yl)methyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dioneHCID 58981145—

Reaction Steps

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 5-nitro-1H-indole-3-carbaldehyde, followed by 1-methyl-1H-imidazole-2-carbaldehyde. Mass: 477.19 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285558B2
Source datasetuspto-grants-2007_10
ORD IDord-13e52587452f4ec28581a223e2049c83
Source noteuspto-grants-2007_10