3-Formyl-2-methylindole → HCID 58981132, compound

HRID 1181754Notes

Reaction equation

HRID 1181754 reaction equation
[NH:1]([C:3]1[N:8]([CH2:9][CH:10]([CH3:12])[CH3:11])[C:7](=[O:13])[N:6]([CH3:14])[C:5](=[O:15])[CH:4]=1)[NH2:2].[CH3:16][C:17]1[NH:18][C:19]2[C:24]([C:25]=1[CH:26]=O)=[CH:23][CH:22]=[CH:21][CH:20]=2.[CH:28]([C:30]1[N:34]([CH3:35])[CH:33]=[C:32]([C:36]#[N:37])[CH:31]=1)=O>>[CH2:9]([N:8]1[C:3]2=[N:1][N:2]([CH2:26][C:25]3[C:24]4[C:19](=[CH:20][CH:21]=[CH:22][CH:23]=4)[NH:18][C:17]=3[CH3:16])[C:28]([C:30]3[N:34]([CH3:35])[CH:33]=[C:32]([C:36]#[N:37])[CH:31]=3)=[C:4]2[C:5](=[O:15])[N:6]([CH3:14])[C:7]1=[O:13])[CH:10]([CH3:11])[CH3:12]

Participants

4

Reactant 3

HCID 731663-Formyl-2-methylindoleHCID 127304775-formyl-1-methyl-1H-pyrrole-3-carbonitrileHCID 193560846-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedione

Product 1

HCID 58981132HCID 58981132, compound

Procedure

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 2-methyl-1H-indole-3-carbaldehyde, followed by 5-formyl-1-methyl-1H-pyrrole-3-carbonitrile. Mass: 470.20 (M+H).

Sources & evidence

ORD record
ord-c2b5d7ed93a5498bb9c175a22ca5a0a5
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

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