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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181757Generated: October 26, 2026

3-Formyl-1H-indole-5-carbonitrile → 3-{[7-isobutyl-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-2-yl]methyl}-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/1181757

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Formyl-1H-indole-5-carbonitrileHCID 28504—
Reactant1-Methyl-2-imidazolecarboxaldehydeHCID 139575—
Reactant6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedioneHCID 19356084—
Product3-{[7-isobutyl-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-2-yl]methyl}-1H-indole-5-carbonitrileHCID 58980943—

Reaction Steps

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 3-formyl-1H-indole-5-carbonitrile, followed by 1-methyl-1H-imidazole-2-carbaldehyde. Mass: 457.14 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285558B2
Source datasetuspto-grants-2007_10
ORD IDord-fbfe4740898148bb99670dda9b7533de
Source noteuspto-grants-2007_10