Potassium Carbonate → 2-[(5-chloro-1H-indol-3-yl)methyl]-7-[(3,5-dimethylisoxazol-4-yl)methyl]-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Participants

Role	Name	HCID	Charge
Reactant	Potassium Carbonate	HCID 11430	—
Reactant	4-(Bromomethyl)-3,5-dimethyl-1,2-oxazole	HCID 12793289	—
Reactant	2-[(5-chloro-1H-indol-3-yl)methyl]-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione	HCID 136334114	—
Solvent	Dimethylformamide	HCID 6228	—
Product	2-[(5-chloro-1H-indol-3-yl)methyl]-7-[(3,5-dimethylisoxazol-4-yl)methyl]-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione	HCID 58981041	—

Reaction Steps

This compound was synthesized by the reaction of 2-[(5-chloro-1H-indol-3-yl)methyl]-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione and 4-(bromomethyl)-3,5-dimethylisoxazole using potassium carbonate as a base in DMF at 80° C. Mass: 519.01 (M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07285558B2
Source dataset	uspto-grants-2007_10
ORD ID	ord-688bdc2f80f64bb89ac92dd25ad9f727
Source note	uspto-grants-2007_10