6-Chloroquinoline-4-carbaldehyde → HCID 69426445, Verbindung

HRID 1181782Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1181782
[CH:1]1([CH2:4][N:5]2[C:10]([NH:11][NH2:12])=[CH:9][C:8](=[O:13])[N:7]([CH3:14])[C:6]2=[O:15])[CH2:3][CH2:2]1.[Cl:16][C:17]1[CH:18]=[C:19]2[C:24](=[CH:25][CH:26]=1)[N:23]=[CH:22][CH:21]=[C:20]2[CH:27]=O.[CH:29]([C:31]1[N:32]([CH3:44])[CH:33]=[C:34]([NH:36][C:37](=[O:43])[O:38][C:39]([CH3:42])([CH3:41])[CH3:40])[N:35]=1)=O>>[Cl:16][C:17]1[CH:18]=[C:19]2[C:24](=[CH:25][CH:26]=1)[N:23]=[CH:22][CH:21]=[C:20]2[CH2:27][N:12]1[C:29]([C:31]2[N:32]([CH3:44])[CH:33]=[C:34]([NH:36][C:37](=[O:43])[O:38][C:39]([CH3:40])([CH3:42])[CH3:41])[N:35]=2)=[C:9]2[C:10]([N:5]([CH2:4][CH:1]3[CH2:2][CH2:3]3)[C:6](=[O:15])[N:7]([CH3:14])[C:8]2=[O:13])=[N:11]1

Komponenten

4

Edukt 3

HCID 31460316-Chloroquinoline-4-carbaldehydeHCID 11629963HCID 11629963, VerbindungHCID 694271711-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione

Produkt 1

HCID 69426445HCID 69426445, Verbindung

Versuchsvorschrift

This compound was made following the procedure described above, starting with 1-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 6-chloroquinoline-4-carbaldehyde, followed by tert-butyl 2-formyl-1-methyl-1H-imidazol-4-ylcarbamate.

Quellen und Nachweise

ORD-Eintrag
ord-a3c82ff63d4343dc9945c2e565536dec
Quelldatensatz
uspto-grants-2007_10
Patentnummer
US07285558B2

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