5-chloro-1H-indole-3-carbaldehyde → HCID 58981155, compound

HRID 1181814Notes

Reaction equation

HRID 1181814 reaction equation
[NH:1]([C:3]1[N:8]([CH2:9][CH:10]([CH3:12])[CH3:11])[C:7](=[O:13])[N:6]([CH3:14])[C:5](=[O:15])[CH:4]=1)[NH2:2].[Cl:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH:21]=[C:20]2[CH:26]=O.[CH3:28][N:29]1[CH:33]=[C:32]([C:34](=[O:37])[CH2:35][CH3:36])[CH:31]=[C:30]1[CH:38]=O>>[Cl:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH:21]=[C:20]2[CH2:26][N:2]1[C:38]([C:30]2[N:29]([CH3:28])[CH:33]=[C:32]([C:34](=[O:37])[CH2:35][CH3:36])[CH:31]=2)=[C:4]2[C:3]([N:8]([CH2:9][CH:10]([CH3:11])[CH3:12])[C:7](=[O:13])[N:6]([CH3:14])[C:5]2=[O:15])=[N:1]1

Participants

4

Reactant 3

HCID 27953745-chloro-1H-indole-3-carbaldehydeHCID 193560846-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedioneHCID 20110104HCID 20110104, compound

Product 1

HCID 58981155HCID 58981155, compound

Procedure

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione and condensing first with 5-chloro-1H-indole-3-carbaldehyde, followed by 1-methyl-4-propionyl-1H-pyrrole-2-carbaldehyde. 521 (M+H).

Sources & evidence

ORD record
ord-8e480efe63d14d60a23b4bb70fac47e1
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

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